Niosome-Encapsulated Gentamicin for Ophthalmic Controlled Delivery
نویسندگان
چکیده
منابع مشابه
Controlled Drug Delivery and Ophthalmic Applications
Controlled drug delivery occurs when a polymer is combined with a drug in a such a way that the release profile is predefined. Conventional forms of drug delivery are based on tablets, eye drops, ointments and intravenous solutions. These delivery systems were characterized by an immediate and non controlled kinetics depending essentially on the properties of tissues to absorb drugs.In the last...
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Article history: Received on: 07/11/2013 Revised on: 21/12/2013 Accepted on: 16/01/2014 Available online: 27/02/2014 Nisoldipine is used for treatment of hypertension and angina pectoris. However, it suffers from very low bioavailability due to its extensive pre-systemic metabolism. This together with its low dose made it excellent candidate for transdermal delivery. Accordingly, the aim of thi...
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Design and development of novel drug delivery system (NDDS) has two prerequisites. First, it should deliver the drug in accordance with a predetermined rate and second it should release therapeutically effective amount of drug at the site of action. Conventional dosage forms are unable to meet these requisites. Niosomes are essentially non-ionic surfactant-based multilamellar or unilamellar ves...
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ژورنال
عنوان ژورنال: AAPS PharmSciTech
سال: 2008
ISSN: 1530-9932
DOI: 10.1208/s12249-008-9105-1